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DermaReverse serum on a yellow gradient background

MEDICAL JOURNAL PUBLISHED · PEER REVIEWED

Skincare developed for skin changing during a GLP-1 journey.

Clinically studied and doctor-developed, DermaReverse addresses 13 distinct measures of skin quality for visibly firmer, smoother, more resilient-looking skin.

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EXPLORE THE CLINICAL STUDY

ONE TIME PURCHASE

13

SKIN QUALITY MEASURES

6 weeks

PLACEBO CONTROLLED STUDY

Patent pending

FORMULATION

Doctor

DEVELOPED

Close-up of dropper applying DermaReverse serum to skin near the eye

WHY DERMAREVERSE EXISTS

Your body is changing.

Your skin deserves support, too.

GLP-1 treatment can be transformative. For some people, it may also be accompanied by visible changes in hydration, elasticity, texture, firmness, and facial skin quality. DermaReverse was developed for this exact moment.

Inside DermaReverse

Two proprietary complexes. One clinically studied serum.

A purposeful blend of peptide technology, a bioavailable retinoic acid derivative, and botanical support optimized for visible impact in one daily ritual.

  • Complex 01

    HP4

    Complementary peptides that support the appearance of firmness, elasticity, hydration, and fine lines.

  • Complex 02

    H2OA

    A bioavailable retinoic acid derivative complex designed to support visible renewal, smoothness, and resilience.

See the full ingredient story
DermaReverse serum bottle surrounded by dishes of its raw ingredients

Published, peer-reviewed clinical study

Results you can see. Research you can trust.

DermaReverse was clinically evaluated in participants using GLP-1 therapy, with visible results observed in as little as three weeks.

  • 13

    Visible skin-quality improvements

  • 3 weeks

    When visible change began

  • 6 weeks

    The complete clinical picture

Read the clinical study

*Study involving participants using GLP-1 receptor agonist or SGLT2 therapy. Results were evaluated at Days 21 & 42. No adverse events were reported during the study period. Individual results may vary. Photographs are of a single study participant and have not been retouched.

Study participant's lower face at Day 42, after six weeks of DermaReverse use
Study participant's lower face at Day 1 baseline, before DermaReverse use
DermaReverse serum on a yellow gradient background
Text stating DermaReverse improved 13 measured skin quality concerns — including texture, wrinkles, hydration, pore size, pigmentation, and elasticity — versus placebo in a peer-reviewed clinical trial
Four-step instructions for using DermaReverse: cleanse skin, apply 3-4 drops to face, neck and décolletage, follow with moisturizer, and add SPF 30+ in the morning
DermaReverse key ingredients — H2OA Complex, HP4 Peptide Complex, ascorbic acid, and aloe vera gel — each shown with a texture swatch and description
Hand holding Aforé DermaReverse serum bottle, 30 mL (1 fl oz), providing approximately 30 days of twice-daily morning and night use
Icons showing DermaReverse's clean formulation: suitable for sensitive skin, clinically tested, paraben-free, no added color or fragrance, made in the USA, glass bottle
Before and after profile photos of a study participant's jaw and neck, before DermaReverse and after 6 weeks of use, from a peer-reviewed clinical study
Close-up of eye area with text noting DermaReverse also studied for fine lines, radiance, surface roughness, hydration, even skin tone, and pigmentation
Close-up of eye with dropper applying serum; text describes DermaReverse as clinically tested in GLP-1 patients and cites a peer-reviewed published clinical study
DermaReverse serum on a yellow gradient background

CHOOSE YOUR ROUTINE

Consistency looks good on you.

A 30 mL twice-daily serum designed to become one steady step in your skincare routine.

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$145 $99 every 30 days

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DermaReverse serum surrounded by four puzzle pieces representing other routine steps

Designed to fit right in

The missing piece in a routine built around change.

One studied serum, designed to earn its place beside the products already in your routine and support the visible skin changes that can come with transformation.

  • Firmness

    Supports visibly firmer, more resilient-looking skin.

  • Elasticity

    Helps improve the look of bounce and suppleness.

  • Hydration

    Supports lasting hydration and a smoother-looking surface.

  • Texture

    Helps refine the appearance of uneven texture and roughness.

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VERIFIED PURCHASER PERSPECTIVE

Real experiences with DermaReverse.

4.7 out of 5

from verified DermaReverse purchasers

Magic in a bottle for me! Love this product. I am seeing positive results quickly. I am also 68 years old and have been taking good care of my skin but gravity is a thing. This product helps to boost my confidence as I am heading to 70. I will be a subscriber!

Linda S. (Verified Purchase)

Even though I’m not using GLP-1 medications, DermaReverse has become a staple in my skincare routine alongside several other Dr. Few products because they consistently live up to their claims. It keeps my skin moisturized, soft, and noticeably smoother, and I’ve seen a real improvement in fine lines. It’s rare to find products that actually deliver, but these truly do.

Amberly (Verified Purchase)

I have been using DermaReverse since it came out. I have aging skin and was hoping this could help. My skin feels great. THEN I had to stop due to cataract surgery for just a few days. Now I really appreciate its' value.

Terri H. (Verified Purchase)

Originally collected from verified purchasers of DermaReverse through Dr. Few Skincare.

DermaReverse serum dropper filled with product, resting on a marble surface

HOW TO USE

Morning & Night Use

1. Cleanse

Begin with clean, dry skin.

2. Apply

Smooth a small amount over the face and neck.

3. Finish

Follow with moisturizer; use broad-spectrum SPF in the morning.

DermaReverse serum

BEYOND THE GLP-1 JOURNEY

Make Aforé part of your glow up routine.

DermaReverse was created around GLP-1-related skin changes, while supporting visible benefits that matter in any considered skin-aging routine: hydration, firmness, elasticity, smoother texture and the look of fine lines.

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DOCTOR DEVELOPED

Developed by a board certified plastic surgeon.

DermaReverse brings real medical journal published, peer-reviewed clinical study to an emerging skincare need with a cosmetic formula built to support the visible quality of skin during meaningful body transformation.

EXPLORE THE CLINICAL APPROACH
Frequently Asked Questions.

Clear answers.
No guesswork.

AFORÉ EARLY ACCESS

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