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A close-up studio shot of DermaReverse serum by Aforé, covered in water droplets, set against a dark olive background.

MEDICAL JOURNAL PUBLISHED · PEER REVIEWED

Made for GLP-1 skin. Published in a medical journal.

DermaReverse is a clinically-studied and medical journal published serum studied in people using GLP-1 therapies to support visibly firmer, smoother, more resilient-looking skin.

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Published, peer-reviewed clinical study

Real skin. Real study. Nothing retouched.

In a six-week, double-blind study, visible improvement began after just three weeks.

  • 13

    Visible skin-quality improvements

  • 3 weeks

    When visible change began

  • 6 weeks

    Even more significant results

*Study involving participants using GLP-1 receptor agonist or SGLT2 therapy. Results were evaluated at Days 21 & 42. Individual results may vary. Photograph above is of a single study participant.

Study participant's lower face at Day 42, after six weeks of DermaReverse use
Study participant's lower face at Day 1 baseline, before DermaReverse use
  • Unretouched
  • Standardized clinical lighting
  • Published in Aesthetic Surgery Journal Open Forum (2025)
Read the published study · doi:10.1093/asjof/ojaf030

Collected from verified purchasers of DermaReverse®.

Close-up of dropper applying DermaReverse serum to skin near the eye

WHY DERMAREVERSE EXISTS

Your body is changing.

Your skin deserves support, too.

GLP-1 treatment can be transformative. For some, it may result in visible changes in hydration, elasticity, texture, firmness, & skin quality. DermaReverse was developed for these exact concerns.

Inside DermaReverse

Two proprietary complexes. One clinically studied serum.

A purposeful blend of peptide technology, gentle vitamin A, and botanical support optimized for visible impact in one daily ritual.

  • Complex 01

    HP4

    Complementary peptides that support the appearance of firmness, elasticity, hydration, and fine lines.

  • Complex 02

    H2OA

    A gentle, water soluble vitamin A complex designed to support visible renewal, smoothness, and resilience.

DermaReverse serum bottle surrounded by dishes of its raw ingredients
DermaReverse serum dropper filled with product, resting on a marble surface

HOW TO USE

Morning & Night Use

1. Cleanse

Begin with clean, dry skin.

2. Apply

Smooth 3-4 drops over the face, neck, and décolletage areas.

3. Finish

Follow with moisturizer; use broad-spectrum SPF in the morning.

DermaReverse serum surrounded by four puzzle pieces representing other routine steps

Designed to fit right in

The missing piece in a routine built around change.

One studied serum, designed to earn its place beside the products already in your routine and support the visible skin changes that can come with transformation.

  • Firmness

    Supports visibly firmer, more resilient-looking skin.

  • Elasticity

    Helps improve the look of bounce and suppleness.

  • Hydration

    Supports lasting hydration and a smoother-looking surface.

  • Texture

    Helps refine the appearance of uneven texture and roughness.

DermaReverse serum

DOCTOR DEVELOPED

Developed by a board certified plastic surgeon.

DermaReverse brings real medical journal published, peer-reviewed clinical study to an emerging skincare need with a cosmetic formula built to support the visible quality of skin during meaningful body transformation.

Frequently Asked Questions.

Clear answers.
No guesswork.

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